The aim of this presentation is to demonstrate how skeletal anchorage, when rationally integrated into clear aligner therapy, does not necessarily increase treatment complexity but, on the contrary, can make treatment simpler, more efficient, and more predictable. The key lies in accurate digital planning that integrates diagnosis, biomechanics, and clinical sequencing into a single therapeutic workflow. Digital planning allows dental and skeletal anatomy to be visualized accurately, interradicular spaces to be assessed, and the ideal position of the miniscrews to be planned. Furthermore, the use of surgical guides can increase placement safety. When used in combination with clear aligners, mini-implants can simplify the treatment of complex cases. They can be used to support maxillary expansion. In sagittal mechanics, they allow dental segments to be distalized or mesialized with greater control, limiting anchorage loss and improving space management. In the management of vertical problems, they represent a fundamental tool for dental intrusion and for controlling the posterior vertical dimension.